Skip to main content
. 2021 Jan 13;153(2):e202012731. doi: 10.1085/jgp.202012731

Table 2. Effect of aPLs on conductance (G) and open probability (PO) of K+ channels in lipid bilayers.

Channel Bilayer N G/pS PO
KcvS PC 10 92 ± 9 −100 mV: 0.40 ± 0.10
KcvS PS 9 120 ± 6a −100 mV: 0.89 ± 0.06a
KcvNTS PC 6 82 ± 12 −100 mV: 0.93 ± 0.01
KcvNTS PS 7 107 ± 5a −100 mV: 0.97 ± 0.01a
KcvPBCV1 PC 8 139 ± 11 +100 mV: 0.01 ± 0.004
KcvPBCV1 PS 6 191 ± 11a +100 mV: 0.12 ± 0.10a
KcvNH PC 3 98 ± 2 +60 mV: 0.47 ± 0.02
KcvNH PS 3 138 ± 4a +60 mV: 0.72 ± 0.06a
KcvMT325 PC 15 34 ± 6 +160 mV: 0.59 ± 0.14
KcvMT325 PG 10 47 ± 6a +160 mV: 0.70 ± 0.08
KcvGLD PC 7 38 ± 4 +160 mV: 0.72 ± 0.07
KcvGLD PG 9 91 ± 16a +160 mV: 0.44 ± 0.05
Kmpv12T PC 10 37 ± 5 −100 mV: 0.21 ± 0.08
Kmpv12T PS 4 62 ± 4a −100 mV: 0.10 ± 0.05

G measured as slope conductance between ± 60 mV. Open probability is presented for each channel for the indicated critical voltage at which a possible difference in PO ± aPLs is most visible. Data are represented as mean ± SD of n independent bilayer recordings.

a

The significance for a difference in G and PO values for PC and PS/PG bilayers is indicated with P values <0.001.