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. 2020 Dec 31;23(3):181. doi: 10.3892/mmr.2020.11820

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Copyright: © Kim et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effects of 9-HIK on NO production and iNOS expression in LPS-treated RAW264.7 cells. RAW264.7 cells were pre-treated with various concentrations of 9-HIK for 2 h, then stimulated with LPS for 18 h. (A) NO production. (B) iNOS mRNA expression levels. (C) iNOS protein expression levels. Data are presented as the mean ± SD; n=3. ^#P<0.05 vs. control; *P<0.05 vs. LPS-treated cells. 9-HIK, 9-hydroxy-isoegomaketone; LPS, lipopolysaccharide; iNOS, inducible nitric oxide synthase; NO, nitric oxide.