Table 2.
Comparision of IFN γ, IL-2, IL-6, IL-10 and IL-17 levels between the pregnancy trimesters.
| Variables | COVID-19 group first trimester (n = 30) | Control group first trimester (n = 30) |
COVID-19 group second trimester (n = 30) |
Control group second trimester (n = 30) |
COVID-19 group third trimester (n = 30) | Control group third trimester (n = 30) |
P valuea |
|---|---|---|---|---|---|---|---|
| IFN γ (ng/dl)(median, IQR) | 17.5 (5) | 15 (3) | 20 (10) | 15 (2.5) | 37.5 (35) | 20 (17.5) | <0.001c |
| IL-2 (pg/ml)(median, IQR) | 80 (20) | 105 (25) | 90(23.75) | 145 (40) | 95 (15) | 110 (20) | <0.001d |
| IL-6 (pg/ml)(median, IQR) | 6.1 (4.3) | 3.3 (1.2) | 6.3 (6.2) | 3.5 (2.3) | 8.1 (15) | 3.8 (1.5) | 0.30 |
| IL-10 (pg/ml)(median, IQR) | 7 (4.5) | 10.8 (5) | 8.8 (3.5) | 9.6 (5) | 9.6 (5.6) | 9.3 (2.6) | <0.001e |
| IL-17 (pg/ml)(median, IQR) | 68 (26) | 104 (19) | 80 (26) | 76 (18) | 84 (35) | 80 (24) | 0.01f |
IFN γ: Interferon gamma, IL: Interleukin.
bPairwise comparisions was performed by Mann-Whitney U test.
Statistical analysis analysis was performed by Kruskal-Wallis test between the groups.
Statistically significant difference was found between the study and control groups in the third trimester (p = 0.001).
Statistically significant differences were found between the study and control groups in the first and second trimesters (p < 0.001 for both).
Statistically significant differences was found between the study and control groups in the first trimester (p = 0.01).
Statistically significant differences was found between the study and control groups in the first trimester (p = 0.04).