Table 1.
Biochemical data of the index patient and her children
| Parameter | Index patient | Daughter (Baseline) | Daughter (after D3 suppl.) | Son (Baseline) | Son (after D3 suppl.) | Reference Range |
|---|---|---|---|---|---|---|
| Urea (mg/dL) | 14 | 16 | 16 | 12 | 13 | 10-40 |
| Creatinine (mg/dL) | 0.6 | 0.4 | 0.5 | 0.5 | 0.4 | 0.5-1.0 |
| Serum calcium (mg/dL) | 11.4 | 10.6 | 10.5 | 11.6 | 11.5 | 8.5-10.5 |
| Serum phosphate (mg/dL) | 3.0 | 2.4 | 3.1 | 4.3 | 4.9 | 2.5-4.5 |
| ALP (IU/L) | 98 | 270 | 92 | 426 | 234 | 80-240 |
| Albumin (g/dL) | 4.0 | 4.3 | 4.3 | 4.2 | 4.9 | 3.5-5 |
| iPTH (pg/mL) | 122.4 | 270 | 63.5 | 351 | 63.9 | 15-65 |
| 25(OH)D (ng/mL) | 57.4 | 4.0 | 24.5 | 6.8 | 30.9 | 20-100 |
| Urinary calcium, mg/24 h | 36 | 76 | 60 | 17.5 | 45 | <100 suggests |
| hypocalciuria | ||||||
| Urinary creatinine, mg/24 h | 854 | 852 | 1080 | 498 | 877 | 11-20 mg/kg |
| Calcium to creatinine | 0.002 | 0.003 | 0.002 | 0.001 | 0.001 | <0.01suggests |
| clearance ratio | hypocalciuria |