Table 1.
Comparison of clinical characteristics of patients with NACKD with those of NKD and ACKD
| NKD [Mean >± SD/Median (IQR) or N (%)] | p Value (NACKD vs NKD) | NACKD [Mean ± SD/Median(IQR) or N (%)] | p Value (NACKD vs ACKD) | ACKD [Mean ± SD/Median (IQR) or N (%)] | |
|---|---|---|---|---|---|
| Number of subjects (N) | 2379 | NA | 75 | NA | 121 |
| Age(years) | 52.7 ± 10.5 | <0.001* | 70.7 ± 10.0 | <0.001* | 64.9 ± 9.0 |
| Duration of diabetes (years) | 6.2 (2.1-11.6) | <0.01 | 14.9(5.7-21.3) | 0.17 | 16.8 (11.0-24.7) |
| Male N(%) | 1409(59.2%) | 0.04* | 53(70.6%) | 0.16 | 96(79.3%) |
| Hypertension N(%) | 741 (31.2%) | <0.01 | 37(49.3%) | <0.01 | 92(76%) |
| Dyslipidemia N(%) | 510 (21.5%) | <0.01 | 30(40.0%) | 0.01 | 60(50.4%) |
| Fasting Blood Glucose (mg/dl) | 179.6 ± 69.2 | 0.09 | 158.6 ± 64.6 | 0.02 | 189.4 ± 95.0 |
| Post prandial Blood Glucose (mg/dl) | 267.0 ± 109.8 | 0.99 | 253 ± 96 | <0.01 | 305.9 124.0 |
| Glycated hemoglobin (% or mmol/mol) | 8.5 ± 2.3 | 0.99 | 8.2 ± 2.3 | 0.21 | 9.0 ± 2.2 |
| Urine Albumin to creatinine ratio (mg/g%) | 11.1(7.3-16.2) | 0.61 | 11.1(7.8-16.4) | <0.01 | 153.8(97.3-198.2) |
| Statin Intake (N%) | 819 (34.5%) | <0.01* | 38(50.6%) | 0.67 | 65(53.7%) |
| ACEI/ ARB Intake (N%) | 475(20%) | <0.01 | 34(45.3%) | 0.20 | 66(54.5%) |
| Past history of coronary artery disease (N%) | Details NA | - | 20/66 (30.0%) | 0.70 | 34/98 (34.6) |
| Previous cerebrovascular accident (N%) | Details NA | - | 3/66 (4.5%) | 0.95 | 8/98 (8.2%) |
Variables showing independent association with NACKD on binary logistic regression have been marked with asterix (*)