Table 3.
Association of final clinicopathologic features with local recurrence.
| Final Clinical and Pathologic Features | Local Recurrence N = 13 | No Local Recurrence N = 181 | P-Value |
|---|---|---|---|
| Age, mean ± SD | 73.9 ± 5.5 | 69.7 ± 7.6 | 0.039 |
| Tumor size (cm), mean ± SD | 0.99 ± 0.54 | 1.04 ± 0.58 | 0.684 |
| Follow-up time (months), mean ± SD | 63.1 ± 23.3 | 44.6 ± 23.4 | 0.010 |
| Histologic type | 0.206 | ||
| Invasive ductal | 12 (6.7) | 167 (93.3) | |
| DCIS | 0 (0) | 3 (100) | |
| Invasive lobular | 0 (0) | 3 (100) | |
| Invasive mammary | 0 (0) | 3 (100) | |
| Invasive mucinous | 0 (0) | 5 (100) | |
| Papillary carcinoma | 1 (100) | 0 (0) | |
| Histologic grade | 0.103 | ||
| 1 | 3 (3.9) | 74 (96.1) | |
| 2 | 7 (7.4) | 88 (92.6) | |
| 3 | 3 (18.8) | 13 (81.3) | |
| Nodal stage | 1.000 | ||
| N0 | 13 (7.3) | 166 (92.7) | |
| N1 | 0 (0) | 12 (100) | |
| Lymphovascular space invasion | 0.191 | ||
| Absent | 11 (6.1) | 168 (93.9) | |
| Present | 2 (16.7) | 10 (83.3) | |
| Extensive intraductal componenta | 1.000 | ||
| No | 13 (6.8) | 178 (93.2) | |
| Yes | 0 (0) | 3 (100) | |
| Tumor size >3 cm | 1.000 | ||
| No | 13 (6.8) | 178 (93.2) | |
| Yes | 0 (0) | 3 (100) | |
| Initial positive margin | 1.000 | ||
| No | 12 (6.7) | 167 (93.3) | |
| Yes | 1 (6.7) | 14 (93.3) | |
| Margin <1 mmb | 1.000 | ||
| No | 12 (6.7) | 167 (93.3) | |
| Yes | 1 (6.7) | 14 (93.3) | |
| Margin <2 mm | 1.000 | ||
| No | 12 (6.9) | 161 (93.1) | |
| Yes | 1 (4.8) | 20 (95.2) |
a
Greater than or equal to 25% DCIS.
b
Includes positive margin.