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. Author manuscript; available in PMC: 2021 Jan 15.
Published in final edited form as: Am J Surg. 2019 Jul 17;218(4):749–754. doi: 10.1016/j.amjsurg.2019.07.011

Table 4.

Local recurrence based on current criteria for addition of whole breast radiation therapy after lumpectomy with intraoperative radiation therapy.

Study Cohort No Local Recurrence N = 181 Local Recurrence N = 13
Suitable for IORT alone (n = 140)
 No recommendation for WBXRT 126 8
 WBXRT recommended but not completed 1 1
 WBXRT completed 4 0
Met criteria for WBXRT (n = 54)*
 TARGIT-A 32 2
 TARGIT-MCC 18 2
*Patients meeting criteria for WBXRT (n = 54) No Local Recurrence N = 50 Local Recurrence N = 4
Met criteria and WBXRT recommended (n = 24)
 TARGIT-A 17 0
 TARGIT-MCC 7 0
Met criteria and WBXRT not recommended (n = 30)
 TARGIT-A 15 2
 TARGIT-MCC 11 2
Met criteria and WBXRT received (n = 17)
 TARGIT-A 13 0
 TARGIT-MCC 4 0

IORT=Intraoperative radiation therapy; WBXRT = whole breast radiation therapy; TARGIT-A = criteria for selective whole breast radiation therapy in TARGIT-A trial; TARGIT-MCC = extended criteria for selective whole breast radiation therapy in current study, inclusive of all TARGIT-A criteria.