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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Neurobiol Aging. 2020 Oct 14;97:89–96. doi: 10.1016/j.neurobiolaging.2020.09.023

Table 1.

Participant characteristics, overall and by metabolic syndrome status (n=350)

Characteristic Total sample n = 350 No Metabolic Syndrome n = 182 Metabolic Syndrome n = 168 p-value
Age, mean (SD), year 64.2 ± 3.3 63.6 ± 3.3 64.4 ± 3.6 0.051
Women, n (%) 252 (72.0%) 128 (70.3%) 124 (73.8%) 0.469
Ethnicity, n (%)
 Dominican 300 (85.7%) 157 (86.3%) 143 (85.1%) 0.875
 Other Caribbean Hispanic 21 (6.0%) 12 (6.6%) 9 (5.4%)
 South American 18 (5.1%) 11 (6.0%) 7 (4.2%)
 Unspecified Hispanic 7 (2.0%) 4 (2.2%) 3 (1.8%)
 Central American 4 (1.1%) 2 (1.1%) 2 (1.2%)
Education, mean (SD), y 10.5 ± 3.9 10.7 ± 3.6 10.1 ± 3.8 0.19
Medication Use, n (%)
 Diabetes 85 (24.3%) 14 (7.7%) 71 (42.3%) <0.0001
  Metformin 73 (20.9%) 14 (7.7%) 59 (35.1%) <0.0001
  Sulfonylurea 20 (5.7%) 2 (1.1%) 18 (10.7%)
  DPP-4i 16 (4.6%) 1 (0.5%) 15 (8.9%)
  PPAR 6 (1.7%) 2 (1.1%) 4 (2.4%)
  GLP-1a 4 (1.1%) 0 (0.0%) 4 (2.4%)
  SGLT2i 2 (0.6%) 1 (0.5%) 1 (0.6%)
  Blood pressure 151 (43.1%) 57 (31.3%) 94 (56.0%) <0.0001
  Lipid-lowering 131 (37.4%) 57 (31.3%) 74 (44.0%) 0.014
APOE-ε4, n (%) 124 (35.4%) 71 (39.0%) 53 (31.5%) 0.144
Fasting glucose, mean (SD), mmol/L 6.1 ± 2.3 5.3 ± 1.3 6.8 ± 2.8 <0.0001
Waist circumference, mean (SD), cm 96.4 ± 11.3 91.7 ± 9.5 101.3 ± 9.6 <0.0001
Triglycerides, mean (SD), mmol/L 6.5 ± 3.4 5.2 ± 2.6 7.8 ± 3.5 <0.0001
High density lipoprotein, mean (SD), mmol/L 3.0 ± 0.8 3.4 ± 0.8 2.6 ± 0.6 <0.0001
Low density lipoprotein, mean (SD), mmol/L 6.1 ± 1.9 6.3 ± 1.8 6.0 ± 2.1 0.212
Systolic blood pressure, mean (SD), mm Hg 134.2 ± 17.8 133.4 ± 18.3 136.7 ± 17.1 0.139
Diastolic blood pressure, mean (SD), mm Hg 82.7 ± 10.2 83.3 ± 11.2 83.5 ± 9.4 0.907

Note: SD = Standard deviation