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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: J Mol Med (Berl). 2020 Jun 18;98(7):1021–1034. doi: 10.1007/s00109-020-01926-7

Fig. 1.

Fig. 1

Circulating EVs and HC-EVs are increased in AH mice. a Quantification of stained circulating EVs via flow cytometry in pair-fed control or AH mice at 8 weeks plus weekly binge. **P < 0.01. b Dynamic light scattering analysis and transmission electron microscopy of isolated circulating EVs from AH mice. c Flow cytometry analysis (dot plot) of calcein+ HC-EVs from pair-fed control or AH mice. d–e Quantification of stained (d) hepatocyte-derived EVs (HC-EVs) or (e) hepatic macrophage-derived EVs (HM-EVs) from pair-fed control or AH mice. **P < 0.01. f Transmission electron microscopy of isolated HC-EVs from AH mice. Values are mean ± SEM