Table 1. Clinical characteristics of patients with paraquat poisoning who received conservative and liberal oxygen therapy (N = 416).
Conservative oxygen therapy n = 334 | Liberal oxygen therapy n = 82 | p-value | |
---|---|---|---|
Age | 51 ± 17.1 | 55 ± 18.3 | 0.050 |
Male sex | 244 (73.1) | 51 (62.2) | 0.052 |
Current smoker | 200 (59.9) | 70 (85.4) | <0.001 |
Chronic lower respiratory diseases | 2 (0.6) | 4 (4.9) | 0.015 |
Malignant neoplasms of lung | 0 (0.0) | 1 (1.2) | 0.197 |
Body temperature during triage (°C) | 36.1 (35.6–36.7) | 36.0 (35.3–36.6) | 0.181 |
Heart rate during triage | 92 (79–106.5) | 92.5 (78–107) | 0.948 |
Respiratory rate during triage | 20 (18–20) | 20 (18–22) | 0.359 |
Mean arterial pressure during triage | 103.3 (89.7–118.0) | 105.8 (93.3–121.0) | 0.390 |
SpO2 during triage (%) | 98 (95–100) | 98 (95–100) | 0.351 |
Glasgow Coma Scale (GCS) | 15 (13–15) | 15 (11–15) | 0.624 |
Urine paraquat concentration (ppm) | 50 (50–50) | 50 (50–50) | 0.462 |
Blood paraquat concentration (ppm) | 8.5 (1.5–10) | 8.6 (1.1–10) | 0.950 |
Blood creatinine level (mg/dL) | 1.8 (1.1–2.8) | 1.7 (1.3–3.6) | 0.252 |
Cyclophosphamide treatment | 159 (47.6) | 37 (45.1) | 0.687 |
Hemoperfusion | 236 (70.7) | 58 (70.7) | 0.990 |
Intubation | 42 (12.6) | 23 (28) | 0.001 |
Signed Do Not Resuscitate (DNR) | 172 (51.5) | 49 (59.8) | 0.179 |
Mortality | |||
3-day mortality | 191 (57.2) | 46 (56.1) | 0.858 |
7-day mortality | 217 (65) | 59 (72) | 0.231 |
28-day mortality | 239 (71.6) | 69 (84.1) | 0.020 |
Overall mortality | 246 (73.7) | 72 (87.8) | 0.007 |
Data are presented as number (percentage), mean ± SD, or median (Q1-Q3).
Abbreviations: SpO2, peripheral oxygen saturation.