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. 2021 Jan 15;16(1):e0245363. doi: 10.1371/journal.pone.0245363

Table 1. Clinical characteristics of patients with paraquat poisoning who received conservative and liberal oxygen therapy (N = 416).

Conservative oxygen therapy n = 334 Liberal oxygen therapy n = 82 p-value
Age 51 ± 17.1 55 ± 18.3 0.050
Male sex 244 (73.1) 51 (62.2) 0.052
Current smoker 200 (59.9) 70 (85.4) <0.001
Chronic lower respiratory diseases 2 (0.6) 4 (4.9) 0.015
Malignant neoplasms of lung 0 (0.0) 1 (1.2) 0.197
Body temperature during triage (°C) 36.1 (35.6–36.7) 36.0 (35.3–36.6) 0.181
Heart rate during triage 92 (79–106.5) 92.5 (78–107) 0.948
Respiratory rate during triage 20 (18–20) 20 (18–22) 0.359
Mean arterial pressure during triage 103.3 (89.7–118.0) 105.8 (93.3–121.0) 0.390
SpO2 during triage (%) 98 (95–100) 98 (95–100) 0.351
Glasgow Coma Scale (GCS) 15 (13–15) 15 (11–15) 0.624
Urine paraquat concentration (ppm) 50 (50–50) 50 (50–50) 0.462
Blood paraquat concentration (ppm) 8.5 (1.5–10) 8.6 (1.1–10) 0.950
Blood creatinine level (mg/dL) 1.8 (1.1–2.8) 1.7 (1.3–3.6) 0.252
Cyclophosphamide treatment 159 (47.6) 37 (45.1) 0.687
Hemoperfusion 236 (70.7) 58 (70.7) 0.990
Intubation 42 (12.6) 23 (28) 0.001
Signed Do Not Resuscitate (DNR) 172 (51.5) 49 (59.8) 0.179
Mortality
    3-day mortality 191 (57.2) 46 (56.1) 0.858
    7-day mortality 217 (65) 59 (72) 0.231
    28-day mortality 239 (71.6) 69 (84.1) 0.020
    Overall mortality 246 (73.7) 72 (87.8) 0.007

Data are presented as number (percentage), mean ± SD, or median (Q1-Q3).

Abbreviations: SpO2, peripheral oxygen saturation.