Table 2. Maternal and perinatal outcomes.
| Cases (n = 405) | Comparison women (n = 694) | OR (95% CI, P-value) | aORa (95% CI, P-value) | |
|---|---|---|---|---|
| Number (% of known) | Number (% of known) | |||
| Maternal Outcomes | ||||
| Admission to ITU | 21 (5) | 1 (0) | 37·9 (5·08–283·2, p = <0.001) | 21.3 (2.78–163.1, p = 0.003) |
| Delivered at time of influenza admission | 114 (28) | |||
| Pregnancy loss | 5 (1) | 2 (0) | 4·33 (0·84–22·4, p = 0.081) | 3·86 (0·39–37.9, p = 0.247) |
| Maternal Morbidityb | 13 (3) | 11 (2) | 2·08 (0·92–4·69, p = 0.077) | 2·23 (0·78–6·43, p = 0.137) |
| Induction of Labour | 167 (43) | 240 (35) | 1·42 (1·10–1·83, p = 0.007) | 1·21 (0·87–1·66, p = 0.253) |
| Mode of deliveryc | ||||
| Cesarean | 151 (38) | 200 (29) | 1·56 (1·20–2·03, p = 0.001) | 1·42 (1·02–1.98, p = 0.040) |
| Emergency caesarean | 76 (19) | 90 (13) | 1·62 (1·16–2·27, p = 0.005) | 1·42 (0·92–2·18, p = 0.110) |
| Assisted vaginal delivery | 33 (8) | 71 (10) | 0·81 (0·52–1·25, p = 0.336) | 0·95 (0·55–1·63, p = 0.853) |
| Perinatal Outcome | ||||
| Preterm Delivery <37 weeks | 52 (13) | 55 (8) | 1·77 (1·19–2·65, p = 0.005) | 1·60 (0·94–2·73, p = 0.083) |
| Very Preterm Delivery <32 weeks | 7 (2) | 11 (2) | 1·13 (0·43–2·93, p = 0.808) | 0·65 (0·16–2·64, p = 0.550) |
| Live birth | 385 (99) | 689 (100) | 0·22 (0·04–1·16, p = 0.074) | 0·14 (0·01–1·34, p = 0.088) |
| Stillbirth/Perinatal death | 5 (1) | 3 (0) | 2·98 (0·71–12·5, p = 0.137) | 3·89 (0·64–23.4, p = 0.139) |
| Admission to neonatal unit | 40 (10) | 32 (5) | 2·39 (1·47–3·87, p = <0.001) | 1·86 (1·01–3·42, p = 0.048) |
| Congenital abnormality | 5 (1) | 10 (1) | 0·89 (0·30–2·63, p = 0.838) | 0·82 (0·21–3·26, p = 0.779) |
| Low birth weight (<10th centile) | 27 (7) | 56 (8) | 0·85 (0·53–1·37, p = 0.507) | 0.95 (0·53–1·70, p = 0.853) |
| Gestation at delivery (weeks), Median (IQR) | 39 (38–40) | 39 (38–40) |
aOR adjusted for Asthma requiring regular steroid treatment, Immunization status, Employment status, and relevant previous pregnancy problems
bComposite of major medical complications including: cardiac arrest, cerebrovascular accident, adult respiratory distress syndrome, disseminated intravascular coagulopathy, HELLP, pulmonary oedema, secondary infection, renal failure, thrombotic event, septicaemia, required ventilation.
cIn women over 24 weeks of gestation (excludes five cases and two comparison women).