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. 2021 Jan 15;7(3):eabc8590. doi: 10.1126/sciadv.abc8590

Fig. 4. Free Nt-α-amino peptides of new NatA substrates pull down IAPs from cell lysates.

Fig. 4

(A to D) Volcano plots from pull-down experiments comparing binders for free Nt-α-amino (Nt-free) and Nt-Ac peptides from SLTM (A) [green in Fig. 3 (B, C, F, and G)], DDX47 (B) [green in Fig. 3 (C and G)], TMEM223 (C) [blue in Fig. 3 (F and G)], and PIGS (D) as control [orange in Fig. 3 (B to D and F to H)] are shown. An FDR < 0.05 and S0 > 2 were applied for the cutoff curve. IAP family members are highlighted in green.