FIGURE 2.

Restricted cubic spline of baseline SBP and 90-day death or dependency, by stroke subtype. Generalized linear mixed model fitted were used with adjustment for study design (fixed effects of head position and cross-over period, random effects of cluster, and random interaction effects between cluster and crossover period) and potential baseline confounders of age, sex, region, history of diabetes mellitus, hypertension, heart failure, atrial fibrillation, coronary heart disease, National Institutes of Health Stroke Scale score, pathological stroke type, premorbid score 0–1 on the modified Rankin scale, aspirin/other antiplatelet treatment, anticoagulant treatment, time from stroke onset to hospital arrival and current smoking. Splines fitted with five knots (percentiles 5th, 27.5th, 50th, 72.5th, 95th) for SBP. Reference SBP 140 mmHg. Solid line indicates odds ratios; dotted line indicates 95% confidence intervals. AIS, acute ischemic stroke; ICH, intracerebral hemorrhage.