Skip to main content
. 2021 Jan 19;131(2):e141594. doi: 10.1172/JCI141594

Figure 3. Antimicrobial transcripts are highly expressed in AMTH17.

Figure 3

(A and B) AMTH17 genes with a log2(fold change) greater than 2 and positively correlated with percentage antimicrobial activity (r > 0.5) were overlapped with an antimicrobial gene list from the GeneCards database. (C and D) Heatmaps of the top 20 highest correlated genes with percentage antimicrobial activity found in the AMTH17 clones with Low (sky blue), Medium (yellow), and High (purple) antimicrobial activity against C. acnes at 6 hours (C) and 12 hours (D). Annotation for percentage antimicrobial activity and correlation coefficient values for each sample and gene are displayed on top (dark blue) and on the left (green). Gene expression values are displayed as z scores of log10-normalized counts.