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. Author manuscript; available in PMC: 2021 Jan 15.
Published in final edited form as: Med Image Comput Comput Assist Interv. 2020 Sep 29;12265:362–371. doi: 10.1007/978-3-030-59722-1_35

Table 1.

Stain Normalization Comparison (Mean ± Standard Deviation) on MITOS-ATYPIA’14 challenge dataset using Structural Similarity Index (SSIM) [20], Feature Similarity Index (FSIM) [21]. The time is the total time taken for normalizing all 500 images.

Methods SSIM FSIM Time (sec)
Reinhard [12] 0.55±0.13 0.63±0.07 6.76
Macenko [7] 0.51±0.08 0.62±0.09 59.40
Khan [4] 0.62±0.18 0.65±0.08 1994.87
Vahdane [17] 0.63±0.11 0.65±0.06 502.04
StainGAN [14] 0.68±0.23 0.69±0.06 69.12
m = 0 (Ours) 0.59±0.32 0.67±0.08 254.06
m = 1 (Ours) 0.73±0.06 0.75±0.11 384.28