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. 2021 Jan 8;2021:1632957. doi: 10.1155/2021/1632957

Table 4.

Comparison of changes in the antioxidant markers during the study period between the placebo and EENO groups.

Variable Baseline After 4 weeks P value Net differences of groups P value
TAC (mM) Control 0.72 ± 0.25 0.63 ± 0.3 P < 0.09 −0.09 ± 0.24 P < 0.39
Intervention 0.7 ± 0.25 0.7 ± 0.3 P < 0.77 0.009 ± 0.29
TOS (µM) Control 9.5 ± 2.3 5.9 ± 2.3 P < 0.001∗∗∗ −3.6 ± 3.3 P < 0.47
Intervention 11.3 ± 3.3 6.9 ± 2.4 P < 0.001∗∗∗ −4.4 ± 4.2
GPX (U/mL) Control 223 ± 115 252.9 ± 107.8 P < 0.17 29.9 ± 7.8 P < 0.54
Intervention 164.2 ± 103.6 173.3 ± 134.4 P < 0.56 9.1 ± 134.8
T-SH (mmol/L) Control 10.1 ± 4.1 5.6 ± 3.2 P < 0.001∗∗∗ −4.5 ± 5.5 P < 0.323
Intervention 13.1 ± 5.3 7.4 ± 4.3 P < 0.001∗∗∗ −5.6 ± 5.5
MDA (mmol/L) Control 1.5 ± 0.14 0.67 ± 0.22 P < 0.001∗∗∗ −0.86 ± 0.26 P < 0.001∗∗
Intervention 1.6 ± 0.13 0.42 ± 0.27 P < 0.001∗∗∗ −1.1 ± 0.28
SOD (U/mL) Control 28.3 ± 8.1 33.8 ± 5.7 P < 0.001∗∗∗ 5.5 ± 4.9 P < 0.32
Intervention 29.3 ± 6.3 37.1 ± 8.4 P < 0.001∗∗∗ 7.8 ± 10

TAC, total antioxidant capacity; TOS, total oxidant status; GPX, glutathione peroxidase; T-SH, sulfhydryl protein; MDA, malondialdehyde; SOD, superoxide dismutase ∗∗(P < 0.01) and ∗∗∗(P < 0.001).