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. 2021 Jan 7;2021:1057186. doi: 10.1155/2021/1057186

Figure 6.

Figure 6

Regulation of SLPI and CLU by cytokines and glucocorticoid. (a–d) The expression level of SLPI (a, c) and CLU (b, d), detected by real-time PCR, in cultured human nasal tissues and A549 cells after 48 hours of stimulation by cytokines or unstimulated control. (e) The upregulated mRNA level of SLPI and CLU in cultured nasal tissues after 48 hours of stimulation by budesonide. (f) Potential glucocorticoid response element in the upstream region of SLPI and CLU. P < 0.05; CLU: clusterin; SLPI: secretory leukoprotease inhibitor; BUD: budesonide; U.S.: unstimulated control; GRE: glucocorticoid response element; TSS: transcription start.