Table 5.
LibDock scores of major active compound-main target molecular docking.
| Number | Compounds | LibDock Score | ||||
|---|---|---|---|---|---|---|
| AKT1 | MAPK3 | VEGFA | SRC | IL6 | ||
| FT3 | Kaempferol | 60.87 | 68.44 | 86.37 | 70.98 | 0.00 |
| FT1 | Isorhamnetin | 60.50 | 112.15 | 123.48 | 92.79 | 67.24 |
| FT11 | (2aR,2'S,4R,4'R,5'S,6aS,6bS,8aS,8bR,9S,11aR,12aR,12bR)-4,4'-dihydroxy-5',6a,8a,9-tetramethylicosahydro-1H-spiro[pentaleno[2,1-a]phenanthrene-10,2'-pyran]-8(2H)-one | 0.00 | 0.00 | 81.20 | 0.00 | 72.51 |
| FT4 | (Z)-3-(4-hydroxy-3-methoxy-phenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide | 94.50 | 110.96 | 94.66 | 99.70 | 85.32 |
| FT10 | Terrestriamide | 0.00 | 0.00 | 96.83 | 96.77 | 88.63 |
| FT14 | Tigogenin | 123.52 | 104.95 | 118.77 | 81.80 | 79.52 |
| FT6 | (3R,8S,9S,10R,13R,14R,17S)-17-((2S,5R)-5-ethyl-6-methylheptan-2-yl)-3-hydroxy-10,13-dimethyl-3,4,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-7(2H)-one | 127.07 | 62.24 | 116.71 | 110.59 | 83.07 |
| FT8 | (Z)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide | 90.15 | 107.96 | 93.94 | 89.87 | 88.15 |
| FT13 | Hecogenin | 0.00 | 0.00 | 76.87 | 0.00 | 0.00 |
| FT7 | (3R,7R,8S,9S,10S,13R,14S,17R)-17-((2R,5S)-5-ethyl-6-methylheptan-2-yl)-3,10-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-7-ol | 95.34 | 113.95 | 94.71 | 87.17 | 92.55 |
| FT2 | Sitosterol | 0.00 | 0.00 | 108.59 | 55.55 | 61.00 |
| FT15 | Terrestrosin D | 0.00 | 0.00 | 151.75 | 167.11 | 0.00 |
| — | Ligand | 86.31 | 88.48 | 47.65 | 133.52 | 72.78 |