Table 1.
Body and heart weight changes in studied groups.
| Groups | Initial body weight (g) | Final body weight (g) | Weight gain (g) | Heart weight (g) | Heart weight/final body weight x 100 |
|---|---|---|---|---|---|
| Control | 25.7 ± 1.6 | 38.1 ± 1.7 | 12.4 ± 1.2 | 0.17 ± 0.01 | 0.45 ± 0.02 |
| ATO (5 mg/kg) | 26.1 ± 1.4 | 31.6 ± 2.1 | 5.5 ± 1.8# | 0.15 ± 0.02 | 0.47 ± 0.05 |
| PTX (100 mg/kg) | 24.8 ± 2.1 | 35.6 ± 2.5 | 10.8 ± 1.4 | 0.17 ± 0.01 | 0.46 ± 0.03 |
| ATO + PTX (25 mg/kg) | 26.7 ± 1.6 | 32.5 ± 1.9 | 5.8 ± 1.2 | 0.15 ± 0.02 | 0.47 ± 0.07 |
| ATO + PTX (50 mg/kg) | 24.6 ± 1.3 | 30.9 ± 1.9 | 6.3 ± 1.6 | 0.15 ± 0.01 | 0.51 ± 0.05 |
| ATO + PTX (100 mg/kg) | 27.1 ± 1.7 | 33.6 ± 2.1 | 6.5 ± 2.2 | 0.16 ± 0.01 | 0.47 ± 0.05 |
The results are expressed as means ± SEM, n = 6 for each group. ≠P < 0.05 vs. control group. ATO: arsenic trioxide (equal 5 mg/kg); PTX: pentoxifylline.