Table 1.

Clinical characteristic and cardiac findings: comparison between 22 children who required critical care (group 1) versus 11 with less severe inflammation (group 2)

Demographic characteristics
Total		Total (%)	Group 1 (critical) (%)	Group 2 (noncritical) (%)	p values#
		33	22	11
Age (year)
	Median (IQR range)	6.0 (3.0–9.0)	7.0 (6.0–10.0)	2.0 (1.3–5.0)	< 0.01
	< 1 year	4 (12.1)	1 (4.5)	3 (27.3)	0.10
	1–5	10 (30.3)	4 (18.2)	6 (54.5)	0.04
	6–10	14 (42.4)	12 (54.5)	2 (18.2)	0.05
	11–18	5 (15.2)	5 (22.7)	0 (0)	0.16
Sex
	M	15 (45.5)	8 (36.4)	7 (63.6)	0.13
	F	18 (54.5)	14 (63.6)	4 (36.4)
Ethnicity
	AA	25 (75.8)	18 (81.8)	7 (54.5)	0.23
	Caucasian	3 (9.1)	0 (0)	3 (27.3)	0.03
	ME	2 (6.1)	2 (9.1)	0 (0)	0.44
	Hispanic	2 (6.1)	1 (4.5)	1 (9.1)	0.56
	Other	1 (3.0)	1 (4.5)	0 (0)	0.67
Comorbidities
	Asthma	7 (21.2)	7 (31.8)	0 (0)	0.04
	Obesity	6 (18.2)	5 (22.7)	1 (9.1)	0.33
	Type 2 DM	1 (3.0)	1 (4.5)	0 (0)	0.67
	Obesity + asthma	3 (9.1)	3 (13.6)	0 (0)	0.28
Clinical presentation
Fever		33 (100)	22 (100)	11 (100)	1.00
GI symptoms
	Vomiting	15 (45.5)	10 (45.5)	5 (45.5)	0.45
	Diarrhea	17 (51.5)	12 (54.5)	5 (45.5)	0.45
	Abdominal pain	17 (51.5)	15 (68.2)	2 (18.2)	0.01
Respiratory distress		4 (12.1)	4 (18.2)	0 (0)	0.18
Skin rash		19 (57.6)	14 (63.6)	5 (45.5)	0.27
Neck tenderness		6 (18.2)	6 (27.3)	0 (0)	0.07
Lymphadenopathy		13 (39.4)	8 (36.4)	5 (45.5)	0.45
KD diagnosis
	Classic	7 (21.2)	6 (27.3)	1 (9.1)	0.23
	Incomplete	6 (18.2)	4 (18.2)	2 (18.2)	0.67
Chest pain		4 (12.1)	4 (18.2)	0 (0)	0.18
Hypotension		17 (51.5)	17 (77.3)	0 (0)	< 0.01
Cardiac involvement
Coronaries
	Dilated	5 (18.2)	5 (27.3)	0 (0)
	Aneurysms	0 (0)
Ejection fraction (%)*
	> 55	17 (53.1)	6 (31.8)	11 (100)
	30–54	13 (40.6)	13 (59.5)	0 (0)
	< 30	2 (6)	2 (9.1)	0 (0)

PICU pediatric intensive care unit, AA African American, ME Middle Eastern, DM diabetes mellitus, GI gastrointestinal

^#Italics indicate significant p values (≤ 0.05)

*Lowest EF during admission, available for 32 patients