Table 2.
Laboratory data in study patients: comparison between 22 children who required critical care (group 1) versus 11 with less severe inflammation (group 2)
| Laboratory data (medians) | |||||
|---|---|---|---|---|---|
| Total number | Total (IQR) | Group 1 (critical) (IQR) | Group 2 (noncritical) (IQR) | Reference value | p values# |
| 33 | 22 | 11 | |||
| C-reactive protein (mg/l) | 171.4 (126.0–291.8) | 267.2 (170.6–316.1) | 126 (38.6–154.5) | < 5 | < 0.01 |
| ESR (mm/h) | 62 (36.5–103.0) | 62 (42.0–112.0) | 70.5 (25.0–95.5) | < 13 | 0.99 |
| Sodium (mMol/l) | 130 (128–133) | 128.5 (127–131) | 133 (132–135) | 136–145 | 0.02 |
| Creatinine (mg/dl) | 0.52 (0.37–0.8) | 0.71 (0.48–1.06) | 0.35 (0.29–0.43) | < 0.6 | 0.04 |
| Albumin (g/dl) | 2.6 (2.3–3.1) | 2.5 (2.2–2.7) | 3.2 (3.1–3.8) | < 4.7 | < 0.01 |
| ALT (U/l) | 32 (20–56) | 40 (20–78) | 23 (18–33) | < 52 | 0.10 |
| AST (U/l) | 40 (33–90) | 44.5 (33–99) | 40 (29–64) | < 39 | 0.34 |
| LDH (U/l) | 397 (329–475) | 390 (330–447) | 432.5 (290–477) | < 271 | 0.77 |
| CK (U/l) | 133 (57–307) | 199 (64–554) | 90 (52–133) | < 233 | 0.07 |
| WBC (K/CUMM) | 13.3 (8.8–18.7) | 13.8 (9.6–18.6) | 9.9 (8.5–19.5) | 4.1–11.3 | 0.61 |
| ALC (K/CUMM) | 900 (600–1900) | 800 (600–1100) | 2100 (1100–3400) | 800–7900 | < 0.01 |
| Fibrinogen (mg/dl) | 488 (429–686) | 607 (433–687) | 480 (428–516) | < 466 | 0.55 |
| PT (s) | 12 (11.4–12.7) | 12.5 (11.4–13) | 11.5 (11.3–12) | < 11.7 | 0.10 |
| PTT (s) | 31.6 (30.1–33.5) | 31.8 (30.6–34.8) | 30.3 (29.6–31.1) | < 33.1 | 0.06 |
| d dimer (mg/l FEU) | 4.3 (2.2–7.9) | 5.1 (4.1–8.2) | 2.1 (1.5–3.2) | < 0.5 | 0.06 |
| Ferritin (ng/ml) | 382 (183.8–828.9) | 681.1 (380.3–869.1) | 121.6 (75.1–272.7) | < 336 | < 0.01 |
| Troponin (ng/l) | 96.5 (27–161) | 131.5 (89–437) | 26 (11–44) | < 17 | < 0.01 |
| BNP (pg/ml) | 966.5 (498–2028) | 1524.5 (555–2301) | 281.5 (25–566) | < 101 | 0.03 |
| IL-6 (pg/ml)* | 22 (15.5–91) | 22 (15.5–91) | N/A | < 6 | |
IQR interquartile, ESR erythrocyte sedimentation rate, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, CK creatine kinase, WBC white blood cells, ALC absolute lymphocyte count, PT prothrombin time, PTT partial thromboplastin time, BNP brain natriuretic peptide, IL-6 interleukin 6
#Italics indicate significant p values (≤ 0.05)
*Only available for 4 patients