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. 2020 Dec 11;7(1):e05703. doi: 10.1016/j.heliyon.2020.e05703

Table 1.

The antiviral activities of LMN or LMN containing plants.

Sources Inhibitory concentration (IC 50) Virus Mechanisms Ref.
LMN 5.9 μg/ml Simplex virus type 1 using RC-37 cells Plaque reduction [30]
Cleopatra mandarin 2.45 Avian influenza A Plaque reduction assay [85]
Heterotheca latifolia >150, 90 and >250 HSV-1, JUNV and DENV-2 Plaque reduction assay (Vero cells) [123]
Lippia junelliana >150, 20 and >250 HSV-1, JUNV and DENV-2 Plaque reduction assay (Vero cells) [123]
Lippia turbinate >150, 14 and >250 HSV-1, JUNV and DENV-2 Plaque reduction assay (Vero cells) [123]
Aloysia triphylla >250 DENV-2, JUNV and HSV-1 Plaque reduction assay (Vero cells) [87]
Gaillardia megapotamica 140.6, 49.8, and 99.1 DENV-2, JUNV and HSV-1 Plaque reduction assay [87]
Pectis odorata 39.6, 36.6, and 71.5 DENV-2, JUNV and HSV-1 Plaque reduction assay [87]
Lippia alba 100 Yellow fever virus Plaque reduction assay [124]
Citrus bergamia 100% inhibition at 0.3% Influenza virus type A H1N1 - [125]
Citrus limonum - Vero cells, HSV-1 Plaque reduction assay [126]
Juniperus communis >10000 HSV-1 Plaque reduction assay [126]
Eucalyptus cinereal 13 μg/ml Coxsakie virus B3 [127]
Lepechinia salviifolia 68.8, 81.9 HSV-1 and HSV-2 Plaque reduction assay [128]
Lepechinia vulcanicola 112, 68.9 HSV-1 and HSV-2 Plaque reduction assay [128]
Lippia alba 10.1, 0.4, 32.6, 21.1, 4.9 DENV-1, 2, 3, 4, YFV 17 DD Plaque reduction assay (Vero cells) [129]
Lippia citriodora Kunth 19.4 μg/ml Yellow fever virus Plaque reduction assay (Vero cells) [129]
Lippia alba 4.3 and 15.2 Yellow fever virus Plaque reduction [86]
Mentha suaveolens 0.87 μg/ml Cytopathogenic murine norovirus Plaque reduction assay [130]
Trachyspermum ammi 80% reduction at 500 μg/ml Japanese encephalitis virus Plaque reduction assay [131]