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. 2021 Jan 11;14:221–237. doi: 10.2147/OTT.S269589

Figure 4.

Figure 4

The inhibitory effect of UTMD-shEZH2 on the migration and invasion of CD133+ HuH7 cells was stronger than that of LIP-shEZH2. (AB) The migration of CD133+ HuH7 cells was detected by wound healing assay (100× Magnification). (CD) The invasion of CD133+ HuH7 cells was detected by transwell assay (250× Magnification). (**P< 0.01, ***P< 0.001, vs LIP-shNC; ^^^P< 0.001, vs UTMD-shNC; ###P< 0.001, vs LIP-shEZH2).

Abbreviations: UTMD, ultrasound-targeted microbubble destruction; LIP, liposome; NC, negative control.