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. 2021 Jan 15;11:1545. doi: 10.1038/s41598-021-81207-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Number of abnormal regions were associated with various clinical parameters. Spearman’s partial correlation analysis with age as nuisance covariate showed that the numbers of aR₀ and aR₁ were related to the duration of illness (r = 0.5822, p = 0.0028; r = 0.42646, p = 0.0386, respectively) (A). The number of aR₀ also was related to the number of AEDs (B) and LSSS (D). AED anti-epileptic drug, QOLIE Quality of life in Epilepsy Inventory, LSSS Liverpool Seizure Severity Scale.