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. 2021 Jan 15;11:1551. doi: 10.1038/s41598-020-80819-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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IFNγ secretion of TLR-stimulated LMCs is correlated with hepatic CD56^Bright CD16^- NK cells. LMCs and PBMCs were stimulated with LPS, R848 or media alone prior to analysis for cytokine production. Total pg/mL for (A) IL-12 and (B) IFNγ. Horizontal bars depict the mean ± SD. N = 16. Comparisons were made using paired t-tests. (C) IL-12 secreted from LMCs stimulated with R848 correlated with the percent hepatic CD56^Bright CD16^- NK cells. (D) IFNγ secreted from LMCs stimulated with R848 correlated with the percent hepatic CD56^Bright CD16^- NK cells. N = 16, calculated using the Pearson’s correlation coefficient.