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. 2021 Jan 15;11:1523. doi: 10.1038/s41598-021-81104-y

Figure 5.

Figure 5

Deletion of the rv3161c gene results in higher resistance to isoniazid and lysozyme. (A) Representative images showing effect of INH and lysozyme on bacterial growth scored by pellet formation. Mtb Erdman WT and ∆rv3161c strains were incubated 2 weeks in Sauton’s medium with 0.02% DMSO or 5 µM C10-IMD in addition to various concentration of INH (left; 0.002–0.064 µg/ml) or lysozyme (right; 3.9–125 µg/ml). (B) Representative images showing effect of INH and lysozyme treatment on bacterial survival scored by spotting bacteria exposed to INH (left; 0.002–0.064 µg/ml) or lysozyme (right; 3.9–125 µg/ml) in the presence of 0.02% DMSO or 5 µM C10-IMD on antibiotic-free 7H10 plates.