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. 2021 Jan 11;8:206–214. doi: 10.1016/j.toxrep.2021.01.005

Table 1.

Incidence of Acute Renal Tubular Necrosis in F344 Rats Given Hydroquinone by Gavage.

Dose Level (mg/kg/day) Males
 Females
0 105 210 420 0 105 210 420
No. examined 12 12 12 12 12 12 12 12
Severity Grade 0 12 12 11 1 12 12 11 3
1 0 0 1 4 0 0 1 6
2 0 0 0 3 0 0 0 1
3 0 0 0 4 0 0 0 2