Skip to main content
. 2020 Dec 3;25(1):575–585. doi: 10.1111/jcmm.16110

Figure 4.

Figure 4

Target gene validation in patient samples. A, Expression of PDCD4, ARL2 and BTG2 was analysed by gene expression profiles (Affymetrix) in AML patients, with normal karyotype, sensitive (n = 27) or resistant (n = 16) to standard chemotherapy treatment combining cytarabine and daunorubicin. The box plot is based on microarray normalized mRNA expression. B, PCA based on selected gene and miRNA expression data were performed in R program using the mixOmics package. The PCA plot of PC2 to PC1 is shown in (B). The correlation plot of the miRNAs and genes used to perform the PCA is shown in (C)