FIGURE 1.

CircPUM1 promotes HCC cells proliferation. A, The expression of circPUM1 in different HCC cell lines was detected by qRT‐PCR assay. B, Knockdown effects of circPUM1 shRNA in MHCC97H and HCCLM3 cells. ***P < .001 vs THLE‐3 cells. C, The proliferation of MHCC97H and HCCLM3 cells with silencing circPUM1 was detected by CCK‐8 assay. D, qRT‐PCR assay showed the expression of circPUM1 in MHCC97H and HCCLM3 cells with overexpressing circPUM1. E, The proliferation of MHCC97H and HCCLM3 cells with overexpressing circPUM1 was detected by CCK‐8 assay. *P < .05, **P < .01, ***P < .001 vs sh‐NC or vector