TABLE 1.
Association of circ‐0000658 expression with clinicopathological features of osteosarcoma
| Feathers | Number | High | Low | P‐value |
|---|---|---|---|---|
| All cases | 60 | 30 | 30 | |
| Age (y) | ||||
| <18 | 41 | 19 | 22 | 0.5796 |
| ≥18 | 19 | 11 | 8 | |
| Gender | ||||
| Male | 26 | 15 | 11 | 0.4348 |
| Female | 34 | 15 | 19 | |
| Tumour size (cm) | ||||
| <5 | 21 | 6 | 15 | 0.0292 |
| ≥5 | 39 | 24 | 15 | |
| Histological subtype | ||||
| Osteoblastic | 5 | 2 | 3 | 0.7076 |
| Chondroblastic | 12 | 6 | 6 | |
| Fibroblastic | 20 | 12 | 8 | |
| Mixed | 23 | 10 | 13 | |
| Distant metastasis | ||||
| Absent | 25 | 7 | 18 | 0.0040 |
| Present | 35 | 23 | 12 | |
| Clinical stage | ||||
| I ~ IIA | 24 | 7 | 17 | 0.0084 |
| IIB ~ III | 36 | 23 | 13 | |
Total data from 60 tumour tissues of osteosarcoma patients were analysed. For the expression of circ‐0000658 was assayed by qRT‐PCR, the median expression level was used as the cut‐off. Data were analysed by chi‐squared test and Fisher's exact test. P‐value in bold indicates statistically significant.