Table 2.
Hazard ratios and 95% confidence intervals for the incidence of composite of end-stage renal disease and all-cause mortality according to the categories of systolic blood pressure among the individuals with chronic kidney disease.
| Categories of SBP (mmHg) | Composite of end-stage renal disease and all-cause death | |||
|---|---|---|---|---|
| Events (n) | Follow-up duration (person-years) | Incidence rate (per 1000 person-years) | Adjusted HR (95% CI)* | |
| Total | ||||
| < 100 (n = 389) | 13 | 2337 | 5.56 (3.23–9.58) | 0.936 (0.535–1.638) |
| 100–109 (n = 1546) | 51 | 9280 | 5.50 (4.18–7.23) | 0.961 (0.708–1.303) |
| 110–119 (n = 4285) | 160 | 25,780 | 6.21 (5.32–7.25) | 0.905 (0.739–1.109) |
| 120–129 (n = 5249) | 227 | 31,426 | 7.22 (6.34–8.23) | 1 (Ref.) |
| 130–139 (n = 6449) | 357 | 38,610 | 9.25 (8.34–10.26) | 1.126 (0.953–1.330) |
| 140–149 (n = 2230) | 191 | 12,989 | 14.70 (12.76–16.95) | 1.443 (1.190–1.751) |
| ≥ 150 (n = 2130) | 226 | 12,374 | 18.26 (16.03–20.81) | 1.502 (1.247–1.811) |
| P for trend | < 0.0001 | |||
| Non-users of antihypertensive agent | ||||
| < 100 (n = 299) | 0 | 1829 | 0 | 0.078 (0.005–1.257) |
| 100–109 (n = 1139) | 15 | 6929 | 2.16 (1.31–3.59) | 0.679 (0.391–1.178) |
| 110–119 (n = 2827) | 57 | 17,193 | 3.32 (2.56–4.30) | 0.889 (0.627–1.259) |
| 120–129 (n = 3020) | 71 | 18,344 | 3.87 (3.07–4.88) | 1 (Ref.) |
| 130–139 (n = 3232) | 103 | 19,698 | 5.23 (4.31–6.34) | 1.173 (0.866–1.587) |
| 140–149 (n = 880) | 45 | 5284 | 8.52 (6.36–11.41) | 1.489 (1.025–2.164) |
| ≥ 150 (n = 777) | 54 | 4627 | 11.67 (8.94–15.24) | 1.744 (1.222–2.490) |
| P for trend | < 0.0001 | |||
| Users of antihypertensive agent | ||||
| < 100 (n = 90) | 13 | 508 | 25.58 (14.86–44.06) | 2.023 (1.158–3.535) |
| 100–109 (n = 407) | 36 | 2351 | 15.32 (11.05–21.23) | 1.303 (0.908–1.871) |
| 110–119 (n = 1458) | 103 | 8587 | 12.00 (9.89–14.55) | 0.948 (0.739–1.217) |
| 120–129 (n = 2229) | 156 | 13,082 | 11.92 (10.19–13.95) | 1 (Ref.) |
| 130–139 (n = 3217) | 254 | 18,912 | 13.43 (11.88–15.19) | 1.084 (0.888–1.324) |
| 140–149 (n = 1350) | 146 | 7705 | 18.95 (16.11–22.29) | 1.371 (1.093–1.720) |
| ≥ 150 (n = 1353) | 172 | 7747 | 22.20 (19.12–25.78) | 1.376 (1.106–1.711) |
| P for trend | 0.0022 | |||
SBP systolic blood pressure, HR hazard ratio, CI confidence interval.
*Adjusted for age, sex, current smoking, alcohol consumption, regular exercise, household income level, body mass index, presence of dyslipidaemia, diabetes mellitus, and urine dipstick positivity for protein. Adjusted HRs (95% CIs) and P-values, considered to be statistically significant in bold font.