Figure 2.

Longitudinal variation in MRI. Longitudinal evolution of (A–C) median and (D–F) peak height MTR in each tissue class (lesions, NAWM, NAGM) as well as (G) total brain volume, (H) white matter, (J) grey matter and (I) lesion volume. The same color represents each individual patient (N = 33) throughout the graphs. All patients were scanned using the same scanner protocol. MTR magnetization transfer ratio, NAWM normal appearing white matter, NAGM normal appearing grey matter, PH peak height, Tot. total, vol. volume, WM white matter, GM grey matter

(Image generated with Rv3.6.1, https://www.R-project.org).