Figure 4.

Correlation of MTR over tissue classes within patients. Correlation of (A) median and (B) peak height MTR in normal appearing tissues versus median and peak height MTR in lesions. Correlation between (C) median and (D) peak height MTR in NAWM versus NAGM in the cross-sectional study population (N = 213). Adjusted r² and P-values result from linear regression with covariates age, gender and MRI protocol. The Bonferroni cut-off for significance of P ≤ 0.05 after correction for multiple testing was 0.00047. MTR magnetization transfer ratio, NAWM normal appearing white matter, NAGM normal appearing grey matter, PH peak height

(Image generated with Rv3.6.1, https://www.R-project.org).