Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 15;12:400. doi: 10.1038/s41467-020-20492-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a KEGG pathway enrichment of the top 2000 hypomethylated DMRs in SCLC. ‘q-value’ refers to one-sided Fisher’s Exact test P value adjusted by Benjamini–Hochberg procedure. b Expression change of genes with hypomethylated DMRs in the KEGG pathways shown in a between LUAD (79) and SCLC (79) patients. The left-to-right order is the same as the top-to-right order shown in a. Two-sided one-sample t-test is used. Sample sizes from left to right for test are 57, 41,24, 30, and 49, respectively. c Expression of SSTR1 in LUAD (79) and SCLC (79) patients. Two-sided Wald test P value is adjusted by Benjamini–Hochberg procedure. d Methylation status of reads mapped to the CHALM-unique hypomethylated DMR found in the SSTR1 promoter region. Only 50 reads are selected for visualization. The methylation levels shown were calculated based on the original dataset. Black circles: mCpG; white circles: CpG. Boxplot definition: line in the box center refers to the median, the limits of box refer to the 25th and 75th percentiles and whiskers are plotted at the highest and lowest points within the 1.5 times interquartile range.