Fig. 2.

Melatonin (MT) attenuates environmental stress-induced fetal growth restriction in mice. Fig. 2 Melatonin (MT) attenuates environmental stress-induced fetal growth restriction in mice. Pregnant mice in Cd and MT + Cd groups received intraperitoneal injection of Cd on GD8. In MT and MT + Cd groups, pregnant mice were treated with MT from GD7 to GD15. Pregnant mice in Ctrl group were treated with saline. n = 10–12 from 10 to 12 different pregnant mice. (A) Fetal weight. (B) Crown-rump length. (C) The rate of FGR. (D) Fetuses per litter. Data are expressed as the mean ± SEM. Multiple comparisons were performed using ANOVA. The post hoc test is executed adopting Bonferroni or Tamhane's T2 method following the result of homogeneity of variance test. **P < 0.01 versus NS group. ^#P < 0.05 versus Cd group.