Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 28;24(1):101996. doi: 10.1016/j.isci.2020.101996

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Combination of 17-DMAG with conventional chemotherapy enhances therapeutic efficacy

(A–C) Tumor growth curve of Rh30 in NSG mice treated with vehicle (n = 10), 17-DMAG (n = 12), VCR/IRN (n = 6), 17-DMAG/VCR/IRN (n = 11) for two weeks (A), Waterfall plot of response to treatment with 17-DMAG, VCR/IRN, and 17-DMAG/VCR/IRN (B), Summary of tumor response to treatment with 17-DMAG, VCR/IRN, and 17-DMAG/VCR/IRN (C). p value is determined by Wilcoxon Rank-Sum test between treatment groups VCR + IRN and 17-DMAG + VCR + IRN.

(D–F) Tumor growth curve of Rh41 in NSG mice treated with vehicle (n = 7), 17-DMAG (n = 8), VCR + IRN (n = 8), 17-DMAG + VCR + IRN (n = 9) for three weeks (D), Waterfall plot of response to the treatment with 17-DMAG, VCR + IRN, and 17-DMAG + VCR + IRN (E), Summary of tumor response to the treatment with 17-DMAG, VCR/IRN, and 17-DMAG/VCR/IRN (F). p value is determined by Wilcoxon Rank-Sum test between treatment groups VCR + IRN and 17-DMAG + VCR + IRN.