Fig. s6.

Representative images of vaginal cytology of mice in (A) proestrus, (B) estrus, (C) metestrus, and (D) diestrus. Three main cell types were detected in vaginal smear samples: nucleated epithelial cells (indicated by magenta color arrows), cornified squamous epithelial cells (indicated by yellow arrows), and leukocytes (indicated by black arrows). The ratio of these cell types present in the smear was used to identify the mice in (A) proestrus, (B) estrus, (C) metestrus, or (D) diestrus as described in the representative results.