Table IV.

Diagnostic values of sphingolipids in patients with advanced ovarian cancer

Variable	Threshold value [ng/100 ml]	Sensi-tivity (%)	95% CI for sensitivity	Speci-ficity (%)	95% CI for specificity	AUC	95% CI for AUC	SE	P-value
Plasma:
C16:0-Cer	315.98	90	0.6645–0.9641	59	0.4899–0.7869	0.818	0.511–0.833	0.071	0.0279
C18:1-Cer	4.81	91	0.6374–0.9855	54	0.4966–0.7836	0.898	0.513–0.919	0.077	0.0230
C18:0-Cer	113.26	79	0.4877–0.9771	59	0.4218–0.8069	0.882	0.520–0.911	0.060	0.0456
RBC:
C18:1-Cer	0.10	90	0.6967–0.9911	49	0.3998–0.6112	0.795	0.523–0.884	0.0715	0.0221

C16:0-Cer – ceramides containing palmitic acid, C18:1-Cer – ceramides containing oleic acid, C18:0-Cer – ceramides containing stearic acid.