Table II.

Results of TNF-α, VEGF, and AFP in the different studied groups

Groups	TNF-α [pg/ml]	VEGF [pg/ml]	AFP [ng/ml]
Normal control	116.8 ±6.8	120.2 ±1.48	3.72 ±0.09
Nano control	110.5 ±9.7	121.50 ±1.42	3.28 ±0.29
Free cur. HD	103.3 ±9.2	126.42 ±1.53	4.00 ±0.27
Free cur. LD	121.3 ±8.4	127.37 ±1.33	4.03 ±0.18
Nano cur. HD	118.0 ±5.2	122.62 ±2.18	4.01 ±0.16
Nano cur. LD	132.4 ±3.4	119.67 ±1.52	3.93 ±0.11
DEN	484.9 ±94.3a	531.27 ±7.76a	55.72 ±0.89a
DEN + Free cur. HD	210.8 ±19.3**	360.53 ±3.93**	17.58 ±0.66**
DEN + Free cur. LD	238.1 ±39.9**	401.38 ±6.58**	19.57 ±0.59**
DEN + Nano cur. HD	142.8 ±11.8**	191.07 ±2.84**	9.12 ±0.26**
DEN + Nano cur. LD	179.3 ±15.7**	256.90 ±3.37**	14.58 ±0.59**

Results are expressed as mean ± SE.

^ap < 0.01 significantly higher than normal

^**p < 0.01 significantly lower than DEN.

TNF-α – tumor necrosis factor-α, VEGF – vascular endothelial growth factor, AFP – α-fetoprotein.