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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Cell Immunol. 2020 Nov 13;359:104244. doi: 10.1016/j.cellimm.2020.104244

Figure 5.

Figure 5.

Degranulating cells are enriched among PD-1− and CD16+ Vδ2 T lymphocytes. Sixteen days after stimulation, CBMC or PBMC were restimulated for 6 hours with plastic-immobilized anti γδ TCR (clone B1.1) in the presence of GolgiPlug (1 μg/ml), and GolgiStop (1 μg/mL). (A) The scatter plot depicts the individual frequencies of CD107a+ Vδ2 T cell, with mean and SD for each group of specimens. (B) The dot plots show the frequency of CD107a+ Vδ2 T cells for a representative donor from each age group after ZOL and BCG stimulation (with paired neonate and infant specimens). (C) The scatter plot shows the individual frequencies of CD107a+ Vδ2 T cells with mean and SD for PD-1+, PD-1− and total Vδ2 T cells. (D) The dot plots display the frequency of CD107a+ cells in the PD-1+ and PD-1− Vδ2 T cell subset for a representative neonatal specimen after ZOL stimulation. * p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001.