Table 2.
Conc. (µM) | BDE-47 | TPHP | IPP | IDDP | TMPP |
---|---|---|---|---|---|
DIV14 (% of control) | |||||
Control | 100 ± 6.9 | 100 ± 5.5 | 100 ± 6.3 | 100 ± 6.9 | 100 ± 6.9 |
0.1 | 97.7 ± 12.7 | 100.0 ± 8.9 | 104.6 ± 8.4 | 106.7 ± 10.6 | 89.9 ± 10.1 |
1 | 93.6 ± 17.4 | 92.2 ± 9.5 | 103.8 ± 8.5 | 108.2 ± 9.4 | 100.2 ± 10.9 |
5 | 93.6 ± 12.7 | 94.4 ± 18.7 | 100.7 ± 17.6 | 94.4 ± 14.3 | 101.1 ± 12.8 |
10 | 84.5 ± 8.8* | 96.1 ± 19.2 | 92.9 ± 11.5 | 82.2 ± 7.6* | 87.2 ± 18.8 |
20 | 76.0 ± 7.8* | 77.5 ± 13.9* | 75.3 ± 0.6* | 81.7 ± 7.5 | |
DIV21 (% of control) | |||||
Control | 100 ± 12.3 | 100 ± 11.2 | 100 ± 11.5 | 100 ± 12.3 | 100 ± 12.3 |
0.1 | 89.2 ± 8.9 | 91.6 ± 13.1 | 91.2 ± 8.7 | 95.2 ± 10.0 | 94.1 ± 12.1 |
1 | 87.8 ± 12.5 | 87.9 ± 13.1 | 90.6 ± 10.9 | 94.7 ± 12.7 | 88.1 ± 14.0 |
5 | 84.4 ± 13.9* | 77.9 ± 18.9* | 78.2 ± 11.5* | 72.1 ± 11.8* | 65.6 ± 6.5* |
10 | 80.0 ± 14.1* | 64.4 ± 22.4* | 54.5 ± 8.8* | 61.7 ± 6.6* | 56.8 ± 10.1* |
20 | 39.3 ± 7.5* | 23.3 ± 13.3* | 59.0 ± 6.3* | 56.0 ± 8.2* |
Data expressed as mean ± SD. Statistical significance is indcated as follow *p < 0.05 (treated vs. control), using one-way ANOVA, Dunnett’s Multiple Comparison Test. followed by Dunnett’s multiple comparison post hoc test including correction for multiple testing. Post hoc test was only performed vs. controls