Table 3.

ToxCast active enrichment generated using the hybrid scoring scheme

logAUC/EF1, Consensus logAUC/EF1, and Total consensus logAUC/EF1 from the orthosteric pocket are calculated, compared, and marked in the same manner as in Table 2, except that the hybrid score (E'_DOCK) is used in the calculation instead of the original docking score (E_DOCK). These values are also compared to the counterparts in Table 2, and highlighted with straight or waved underline when they are better or worse than the counterparts in Table 2

Consensus logAUC/EF1 (and Total consensus logAUC/EF1) is in bold/italic font when it is 10% larger/smaller than that from the best performing structure, and in a normal font in rest cases where it is considered to be comparable