Table-3.

Median score of various histopathological parameters of MEBO- and honey-treated wounds in healthy and immunocompromised dogs (n=12).

Parameter	Healthy dogs
	Time (Days)	Honey	MEBO	Control
Re-epithelialization	7	0.50	0.00	0.50
	14	3.00*	3.00	3.00
	21	3.00	3.00*	3.00
Granulation tissue	7	3.00	3.00	2.00
	14	1.00	1.00	1.00
	21	1.00	1.00	1.00
Collagen accumulation	7	3.00	3.00	2.00
	14	3.00	3.00	3.00
	21	3.00	3.00	3.00
Inflammatory cells	7	3.00	3.00	2.50
	14	0.50	0.50*	0.00*
	21	0.00	1.00	0.00
Angiogenesis	7	3.00	3.00	3.00
	14	1.50	2.00	1.00
	21	1.00	1.00	1.00
Ulcer	7	3.00	3.00	2.50
	14	0.00	0.00	0.00
	21	0.00	0.00	0.00
Immunocompromised dogs
Re-epithelialization	7	0.00	0.00	0.00
	14	1.00	0.00	1.00
	21	3.00	1.00	2.00
Granulation tissue	7	3.00	3.00	3.00
	14	2.00	2.00	2.00
	21	1.00	0.50	2.00
Collagen accumulation	7	3.00	2.00	2.00
	14	3.00	3.00	3.00
	21	3.00	1.50	2.00
Inflammatory cell	7	3.00	3.00	3.00
	14	2.00	2.00	1.50
	21	0.00	2.50	1.00
Angiogenesis	7	3.00	3.00	3.00
	14	1.50	2.00	2.00
	21	1.00	0.50	2.00
Ulcer	7	3.00	3.00	3.00
	14	2.50	3.00	2.00
	21	1.00	2.50	1.00

^*Indicates significant differences in the evaluated parameters between control and immunocompromised groups (p<0.05)