Figure 2. Body weight changes in AOM/DSS-treated mice. (A) Administration protocol. The mice in groups 1 and 3 were administered Fx-oil at 30 mg Fx/kg body weight (bw) 3 times per week for 14 weeks (black arrows). The mice in groups 2 and 4 control groups were given the equivalent volume of control-oil (gray arrows). The mice in groups 1 and 2 were treated with AOM/DSS. Saliva in mice was collected under isoflurane anesthesia after pilocarpine injection (white arrow heads). (B) Body weight changes from the day just before AOM administration to the sacrifice day. Means±SE (n=9-10). A significant difference was found between groups 1 and 2 (97 days after AOM injection): *p<0.05 by one-way ANOVA with post-hoc Tukey-Kramer test.