Table 3.

Binary clinical classification.

Organ/system	Value	Rule	Clinical Interpretation
Lung	1, 0	1 if severity grading 4–2 and 0 if severity grading 1–0	Lung disease
Heart	1, 0	1 if cTnT > reference value or NT-proBNP gender specific reference value or Arrhythmia	Heart disease
Liver	1, 0	1 if ALT and AST > gender-specific reference value	Liver disease
Pancreas	1, 0	1 if lipase and/or pancreatic amylase > or < specific reference value	Pancreas disease (either inflammation or depletion)
Kidney	1, 0	1 if creatinine > gender-specific reference value	Kidney disease
Lymphoid system	1, 0	1 if NK cells < reference value or CD4 lymphocytes < reference value	Innate and adaptive immune deficit
Olfactory/gustatory system	1, 0	1 if hypogeusia or hyposmia	Olfactory and Gustatory deficit
Clotting system	1, 0	1 if D-dimer > 10× W/wo low fibrinogen level (with high basal level)	Thromboembolism
Pro-inflammatory cytokines system	1, 0	1 if IL6 > reference value or LDH and CRP > reference value	Hyperinflammatory response

cTnT cardiac Troponin T, NT-proBNP N-terminal (NT)-pro hormone BNP, ALT Alanine transaminase, AST Aspartate transaminase, CD4 CD4+ T cells, NK Natural killer, IL6 Interleukin 6, LDH lactate dehydrogenase, CRP c-reactive protein.