Table 2.
Median change (range) | Rituximab | Control | p value |
---|---|---|---|
Absolute change in FVC (% predicted, posttreatment – baseline) | −3.0 (−11, 21) | 2.0 (−14, 25) | 0.03* |
Absolute change in DLCO (% predicted, posttreatment – baseline) | −3.0 (−10, 12) | 4.5 (−30, 36) | 0.046* |
Change in CT score (posttreatment – baseline) | 0 (−9, 1) | 0 (−5, 7) | 0.5 |
Change in average daily prednisone dose (posttreatment – baseline) a | −0.5 (−2.0, 1.0) | 0 (−2.0, 1.0) | 0.02* |
Abbreviations: CT, computed tomography; DLCO, diffusing capacity of carbon monoxide; FVC, forced vital capacity.
Units based on aforementioned scale from 0 to 3 (0 = no prednisone use, 1 = prednisone ≤10 mg/d, 2 = prednisone 10‐20 mg/d, 3 = prednisone 20‐60 mg/d).
p < 0.05.