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. 2020 Dec 4;3(1):3–7. doi: 10.1002/acr2.11210

Table 2.

Changes in pulmonary function, imaging, and prednisone use in rituximab versus control groups

Median change (range) Rituximab Control p value
Absolute change in FVC (% predicted, posttreatment – baseline) −3.0 (−11, 21) 2.0 (−14, 25) 0.03*
Absolute change in DLCO (% predicted, posttreatment – baseline) −3.0 (−10, 12) 4.5 (−30, 36) 0.046*
Change in CT score (posttreatment – baseline) 0 (−9, 1) 0 (−5, 7) 0.5
Change in average daily prednisone dose (posttreatment – baseline) a −0.5 (−2.0, 1.0) 0 (−2.0, 1.0) 0.02*

Abbreviations: CT, computed tomography; DLCO, diffusing capacity of carbon monoxide; FVC, forced vital capacity.

a

Units based on aforementioned scale from 0 to 3 (0 = no prednisone use, 1 = prednisone ≤10 mg/d, 2 = prednisone 10‐20 mg/d, 3 = prednisone 20‐60 mg/d).

*

p < 0.05.