Table 1. The univariate and multivariate Cox regression analysis of the patients from The Cancer Genome Atlas (TCGA).

Parameters	Univariate			Multivariate
	HR	95% CI	p-value	HR	95% CI	p-value
Recurrence (yes vs no)	2.405	[1.709–3.385]	<0.001	2.449	[1.738–3.450]	<0.001
Age (≤65y vs >65y)	1.157	[0.860–1.558]	0.336
Gender (male vs female)	1.047	[0.782–1.400]	0.759
Risk score	2.216	[1.635–3.004]	<0.001	1.897	[1.329–2.709]	<0.001
T stage	2.455	[1.697–3.553]	<0.001	1.827	[1.827–1.156]	<0.01
N stage	2.546	[1.900–3.411]	<0.001	2.139	[1.517–3.017]	<0.001
M stage	1.027	[0.747–1.414]	0.868
TNM stage (I-II vs III-IV)	2.686	[1.973–3.658]	<0.001	1.963	[1.579–3.141]	0.155
Number-pack-years-smoked	1.028	[0.716–1.475]	0.881