Table 2. Distribution of 51 patients in the five groups considering the probability of presenting bacterial meningitis based on the results of microbiological and molecular CSF.
| Definition Number of patients | Positive by PCR | Positive by culture | PCR amplicon sequencing |
|---|---|---|---|
| G1 Confirmed bacterial meningitis n=4 | 3 | Klebsiella pneumoniae (n=2) Enterobacter cloacae (n=1) Staphylococcus haemolyticus (n=1) | K. pneumoniae (n=1) E. cloacae (n=1) S. haemolyticus (n=1) |
| G2 Probable bacterial meningitis n=5 | 3 | - | Variovorax boronicumulans (n=2) Enterococcus cecorum (n=1) |
| G3 Possible bacterial meningitis n=10 | 4 | - | Granulicatella adiacens (n=1) Pseudomonas aeruginosa (n=1) *Unidentified (n=2) |
| G4 Bacterial meningitis unlikely n=24 | 13 | - | G. adiacens (n=1) Variovorax paradoxos (n=1) P. aeruginosa (n=1) Acinetobacter baumannii (n=1) Enterobacterales (n=3) *Unidentified (n=6) |
| G5 No meningitis n=8 | 1 | - | *Unidentified (n=1) |
| Total n=51 | 24 (47%) |
CSF: cerebrospinal fluid; *Nine samples displayed a second band in the gel, which made sequencing impossible.