Figure 5.

Plasma metabolomic profile in young and old mice subjected to I/R injury or sham operation – Heatmap, negative mode: Heatmap and hierarchical clustering analysis generated for the metabolites (identified in negative mode) that have a significant difference in either “Sham_Old vs Sham_Young” or “I/R_Old vs I/R_Young.” We computed a z‐score, where we adjusted the data by feature, to have a mean of zero and a standard deviation of 1. The resulting heatmap presents the features (reported on the right side) in rows and samples in columns, both of which are clustered